Journal Published Flawed Stem Cell Papers Despite Serious Misgivings About Work

sciencehabit writes: As two discredited, and now retracted, stem cell papers have produced an almost unimaginable fallout — a national hero accused of scientific fraud, the revamping of one of Japan's major research institutes, and the suicide of a respected cell biologist — researchers have privately and publicly asked how Nature could have published work that, in retrospect, seems so obviously flawed. Another piece of the puzzle has now come to light. The Science news team received a copy of email correspondence between a Nature editor and Haruko Obokata, the lead author of the papers, which indicates the work initially received as rocky a reception there as at two other journals, Cell and Science, that had rejected the work previously. The email, dated 4 April 2013, includes detailed separate criticisms of the two papers and suggestions for new data to support the authors' claims of a simple and novel way to make stem cells that could form the myriad cell types within a body. The Nature editor rejected the papers, but left open a window, writing, "Should further experimental data allow you to address these criticisms, we would be happy to look at a revised manuscript." The two papers were published 10 months later.

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